Thrombin Inhibition in Subarachnoid Hemorrhage

Thrombin activity in cerebrospinal fluid after subarachnoid hemorrhage.

Cardiac Complication Following Subarachnoid Hemorrhage

Besides its severe neurological injuries, spontaneous subarachnoid hemorrhage (SAH) commonly causes cardiac complications. These complications could include three different aspects of cardiac diseases, that is, electrocardiographic abnormalities, myocardial injuries, and left ventricular dysfunction. These complications not only may lead to misdiagnosis of SAH as myocardial infarction, but also...

imaging consideration in subarachnoid hemorrhage

this presentation aims to focus on different types of sub arachnoid hemorrhage (diffuse ,central and perimesencephalic) with different etiology and their important imaging considerations that are important to know when a radiologist encounter to a case of sub arachnoid hemorrhage.

Thrombin inhibition by argatroban ameliorates early brain injury and improves neurological outcomes after experimental subarachnoid hemorrhage in rats.

BACKGROUND AND PURPOSE We investigated the role of thrombin in early brain injury after subarachnoid hemorrhage (SAH). METHODS The standard intravascular perforation model was used to produce experimental SAH in Sprague Dawley rats. Low-dose (0.3 mg/h) and high-dose (0.9 mg/h) argatroban, a direct thrombin inhibitor, were evaluated for effects on brain edema, blood-brain barrier (BBB) disrupt...

Subarachnoid Hemorrhage.

Aneurysmal subarachnoid hemorrhage (SAH) is a neurological emergency with high risk of neurological decline and death. Although the presentation of a thunderclap headache or the worst headache of a patient's life easily triggers the evaluation for SAH, subtle presentations are still missed. The gold standard for diagnostic evaluation of SAH remains noncontrast head computed tomography (CT) foll...